DROTAVET 20ml antispastic drotaverine hydrochloride 20 mg/ml for racing horses, dogs, cats

DROTAVET 20ml antispastic drotaverine hydrochloride 20 mg/ml for racing horses, dogs, cats - Pet Shop Luna SRL

Romvac

€ 12.90 

Composition
Active substance: Drotaverine hydrochloride 20 mg / ml;
Excipient (deionized water) ad. up to 1 ml

Target species
Leisure or racing horses, dogs and cats.

Pharmacological action
Drotaverine is an antispasmodic whose action is based on the significant inhibition of the enzymatic activity of phosphodiesterase (PDE), responsible for AMP-cyclic hydrolysis (cAMP) to AMP. Inhibition of phosphodiesterase leads to an increase in the concentration of cAMP that influences the decrease in cytoplasmic concentrations of Ca2 + ions in the muscle fiber. This explains the effect of drotaverine as a calcium antagonist and contributes to its antispasmodic effect. The relaxing effect of drotaverine on smooth muscle is independent of the type of vegetative innervation. It is equally effective on the smooth muscles of the postdiaphragmatic digestive tract, bile ducts, urogenital tract and vascular system. Due to its vasodilating effect, it improves the blood supply to the tissues. Drotaverine crosses the placental barrier.

Directions
The product is used as an antispasmodic in: adjuvant treatment of digestive disorders (abdominal colic, gastric or duodenal ulcer, gastritis, spastic enteritis, colitis, pancreatitis, spastic constipation, flatulence, spasms of the sphincters cardia and pylorus, spasms of the smooth muscles of the bile ducts, gallstones, cholecystitis); spasms of the smooth muscles of the urinary tract (kidney stones, ureteral stones, skin, cystitis); diseases of the genital tract (tetanic uterine contractions, imminent abortion), in dogs, cats and leisure horses and racing. The spasmolytic action of the product also reduces the pain until it is canceled.